Clinical Features of NMDAR Ab-mediated Encephalitis
نویسندگان
چکیده
Investigators from University of Oxford, Birmingham Children's Hospital, Guy's and St Thomas', London, UK, performed a prospective surveillance study in children with NMDAR-Ab-mediated neurological disease reported from Nov 2010 to Dec 2011.
منابع مشابه
O 21: A Case of Anti-NMDA Receptor Encephalitis Who Presented with Status Epilepticus
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is is most common form ofimmune-mediated encephalitis with prominent neurologic and psychiatric features at disease onset. We describe a 16 years old patient who presented with fever and status epilepticus. His MRI sequences was normal. Anti-NMDAR antibodies were detected in the CSF. MRI, CT and other studies didn,t show any tum...
متن کاملN-methyl-D-aspartate receptor antibody-mediated neurological disease: results of a UK-based surveillance study in children
OBJECTIVE N-methyl-D-aspartate receptor antibody (NMDAR-Ab) encephalitis is a well-recognised clinico-immunological syndrome that presents with neuropsychiatric symptoms cognitive decline, movement disorder and seizures. This study reports the clinical features, management and neurological outcomes of paediatric NMDAR-Ab-mediated neurological disease in the UK. DESIGN A prospective surveillan...
متن کاملCSF IgA NMDAR antibodies are potential biomarkers for teratomas in anti-NMDAR encephalitis
OBJECTIVE To evaluate the presence of immunoglobulin A (IgA) subtype of anti-NMDA receptor (NMDAR) antibodies (IgA-NMDAR-Abs) in the CSF of patients with immunoglobulin G (IgG)-NMDAR-Ab encephalitis and to describe the potential association with a specific clinical pattern. METHODS The retrospective analysis for the presence of IgA-NMDAR-Abs in 94 CSF samples from patients with anti-NMDAR enc...
متن کاملDiagnostic value of CSF findings in antibody-associated limbic and anti-NMDAR-encephalitis
PURPOSE In people with suspected inflammatory CNS disease, cerebrospinal fluid (CSF) is commonly analyzed. Antibody-associated limbic encephalitis (ab-LE) and anti-NMDAR-encephalitis are recognized as two major syndromes of autoimmune epilepsies. Here, we investigated the diagnostic value of CSF findings in these two entities. METHODS We reviewed patients from our tertiary epilepsy centre wit...
متن کامل[Antibody-related neuroimmunological disorders: update on the diagnosis and treatment].
Varieties of autoantibodies are known to relate to autoimmune neurological disorders as the diagnostic and therapeutic markers. Some of them affected directly to the pathomechanisms of neurological diseases. Recently several autoantibodies with such roles have been reported showing the common characters as recognizing cell surface antigens. Among them, anti-aquaporin 4 antibody (AQP4-Ab) in neu...
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عنوان ژورنال:
دوره 29 شماره
صفحات -
تاریخ انتشار 2015